The health reports of the MyHeritage DNA Health test (and Health upgrade) are based on robust scientific research conducted by the MyHeritage Science team, and peer-reviewed academic papers. Your DNA is read in MyHeritage’s lab using a new DNA chip — Illumina’s Global Screening Array (GSA), customized by MyHeritage. Illumina states that it uses trusted Infinium technology to deliver call rates of over 99% and reproducibility of over 99.9%.
To further ensure the accuracy of your results, we confirm significantly increased genetic risk results for most conditions using Sanger sequencing, the industry-standard in molecular testing. This step substantially reduces the potential for false positives.
The test determines only your genetic risk and does not reflect your overall risk for developing or passing on a genetic condition. Environmental and lifestyle factors influence your level of risk in addition to your DNA.
The test covers an extensive range of genetic variants but does not cover every gene and every variant associated with each condition tested. As the test looks at only some of the variants for a condition, having a personal or family health history of the condition may warrant more thorough testing. If you have a family history of one or more of the conditions we test for, you should speak to a genetic counselor or a healthcare provider to discuss whether additional testing, screening, and/or evaluation may be appropriate.
When creating polygenic risk reports, we analyze thousands of variants across your entire genome and combine the results of this analysis to calculate your polygenic risk score (PRS). PRS is the most comprehensive approach for estimating genetic risk for conditions that are caused by a combination of variants on multiple genes.
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