Here's what I have tried so far: reinstalling (with newest version), uninstalling and reinstalling, reimporting from the exported zip and renaming it, deleting all the pictures...  I even installed it on my sister's new laptop and although it ran really fast, saving the project still took 30 minutes.

 I am running Vista with Service Pack 2 (just installed two weeks ago, but like I said, the problems didn't start until this Tues).  All I can think of that I might have done is that I turned off Auto-Save after the first slow save (because auto-save was taking 1-3 min and freezing up my computer) and right after this the problem escalated. But turning auto-save back on didn't help at all, since it now locks up the program too.

Here are the stats of my project: 949 individuals, 369 families, 12 sources, 24 notes, 212 photo records, file size 1227.7 kb, compression-Yes, and last loading time was 216.5 seconds (previously it had been 10-15s).

My photos are really big, but they had never slowed it down before, and I didn't add any new ones in before this problem started.  And like I said, the other project still works perfectly (although, I can't "save as" with that one either, as it tells me the paths are invalid for any new names I give it).   I didn't install any new programs this week, Windows is up to date, and I defragged and scanned last week with Mcafee, Avast, and Malwarebytes--so I really doubt it's a virus.  So has this happened to anyone else?  Is my project corrupted somehow?

Thanks for the listen.  I've worked on this for the past eight hours today, and I'm out of ideas.